Artificial Nerve Conduits Market Size to Attain USD 5.79 Bn by 2034

Artificial Nerve Conduits Market Companies, Trends and DROs

The global artificial nerve conduits market was estimated at US$ 2.37 billion in 2023 and is projected to grow to US$ 5.79 billion by 2034, rising at a compound annual growth rate (CAGR) of 8.35% from 2024 to 2034. The growing demand to repair damaged nerves with improved nerve regeneration potential over longer distances is contributing to the adoption of the artificial nerve conduits market.

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Market Overview

An artificial nerve conduit is a tubular structural device us to repair nerve injuries by connecting the severed ends. Based on current research, artificial nerve conduits have the potential to improve nerve regeneration over longer distances, more than 3 cm in length. It is easily available and fabricated compared to autografts. Although, there are limitations with the use of autografts such as donor experiencing loss-of-function, formation of painful neuromas, structural difference between donor and recipient graft and lack of graft material, which are completely resolved in artificial nerve conduits, as it allows easy specification of conduits size and its mass-production.

Artificial Nerve Conduits Market Trends

• In February 2024, a research team from Ruhr University Bochum and Tu Dortmund University, both in Germany, created an artificial cell environment that promotes nerve regeneration.
• In May 2024, the National Institute of Health (NIH) granted $2.6 million to scientists at Albany Medical College to study the role of a specific protein in peripheral nerve disorder.
• In October 2024, the National Multiple Sclerosis Society committed $4.6 million in multi-year funding to boost the development strategies for repairing the nervous system and protecting it from further damage. The focus is also on restoring the lost sensory functions.

Technological Advancements to Open Doors as Opportunity

Innovative development of tissue engineering techniques is expanding, Nerve guidance conduits are expected to facilitate nerve repair. The nerve conduit technologies provide design strategies, biomaterial selection, fabrication techniques and various microenvironment that replicate the natural process of regeneration. Likewise, other development under neural repair technologies includes nerve regeneration bridging technology, electrical stimulation technology and stem cell therapy. Combining all together offers novel methods and opportunities for repairing nerve defects. Moreover, there is still a requirement for research and development to improve the effectiveness and feasibility.

High Cost Restrains the Market Expansion

Cost expenses play a vital role in surgeries. The cost range of nerve graft or repair ranges somewhere between $4,073 to $13,579. The success rate of nerve repair surgery is based on the type and severity of the nerve injury. Another factor for the surgery to cost so high is the skill and experience of the surgical team, as nerve surgery is a complex operation dealing with the brain and spinal cord, therefore an expert with extensive training and high experience is a must. Besides this, the hospital must be equipped with the latest technologies to deal with this complex procedure.

Regional Insights

Prevalence of peripheral nerve injuries drives North America.

North America dominated the artificial nerve conduits in 2023. The dominance of this region is observed due to the growing incidence rate of peripheral nerve injury in America. Every year more than half a million Americans suffer from peripheral nerve injuries that require surgical treatment. Moreover, North America stands out as the leading region for its healthcare facilities and professional experts in the field.

Government initiative drives market in Europe.

Europe is anticipated to grow at the fastest rate over the forecast period. Government initiatives and research institutes support this region in the growth and development of the artificial nerve conduits market by providing financial support to the institutes and universities. Moreover, technological advancement is rising in the region making an impact on the healthcare industry and the nerve regeneration field and propelling the growth of the artificial nerve conduits market.

Segmental Insights

By material, the synthetic segment accounted for the highest market share in 2023. Over the years the synthetic polymer segment has developed in designs and material selection which makes it the dominating and widely used material for nerve conduit.

The biologics segment is estimated to grow at the fastest rate over the studied period. The biological materials are derived from polysaccharides. In the laboratory, when a researcher strips the polysaccharide chain of any genetic markers and leaves the cell structure as it is, the spiral-like structure with nanofibers lining promotes cell growth at the located area.

By nerve, the contact guidance dominated the artificial nerve conduit market by holding the largest market share. This is because contact guidance is used as a directional structure which provides an elongated direction for cells to grow. It also offers various substances with conduits to provide directional physical and biological signals, with the help of similar multiple strategies, the future conduit can be expected to improve in its ability.

The channel guidance segment is anticipated to grow at the fastest rate in the artificial nerve conduit market over the projected period. The growth in this segment is linked with the factor of nerve channel guidance implementation provider physical support to the spinal cord injury. The design of channel guidance assists in repairing by protecting spinal cord injury.

By electroactivity, the electroactive segment led the artificial nerve conduit market in 2023. The dominance of the segment is driven by its property to effectively repair peripheral nerves. The design and application of the biodegradable non-invasive electrical system result in benefiting patients from artificial nerve catheter treatment.

The non-electroactivity segment is estimated to grow at the fastest rate over the studied period. With the use of electroactive in the nerve repair treatment, the results will not that as effective and as prominent impacting the recovery of the patient.

By application, the peripheral nerve repair segment contributed the biggest market share in 2023. The growth of this segment is due to artificial nerve conduits, which offer an alternative to nerve autografts to repair peripheral nerve injuries.

The spinal cord injury segment is estimated to grow at the fastest rate over the studied period. On a usual point, injuries to the brain or spinal cord are hard to heal due to the formation of fluid-filled cavities and scares that prevent tissue regeneration. This can be resolved by creating an artificial nerve conduit microenvironment that provides a natural growth of cells and nerve growth.

By end-user, the hospital segment dominated the artificial nerve conduit market in 2023. In a hospital setting, the surgery and healthcare professionals help ease neuropathic pain, perform surgery if needed, and repair or remove certain nerves to reduce or eliminate pain. Hospitals also offer psychological counselling to cope with emotional stress related to neuropathic pain.

The clinics segment is anticipated to grow at the fastest rate during the forecast period. This segment is still a growing factor due to clinical results regarding artificial nerve conduits are particularly inferior to autografts. Currently, on a clinical base, there is no adequate treatment available to repair a large gap defect in a nerve.

Recent Developments

• In September 2024, Axogen, Inc., a global leader in developing and marketing innovative surgical solutions for peripheral nerve injuries, announced its completion of a Biologics License Application (BLA) which is approved by the U.S. Food and Drug Administration (FDA) for Avance Nerve Graft®.
•  In March 2024, Neuraptive Therapeutics Inc. dedicated medical products and therapeutics to repair and regenerate peripheral nerves company. FDA approves the company’s NTX-001 surgical kit for peripheral nerve repair.

Top Companies in the Artificial Nerve Conduits Market

• Axogen
• Axonics
• CollPlant Biotechnologies
• Cook Medical
• Cytograft Tissue Engineering
• FibroGen
• Integra LifeSciences
• Eton Biological
• KeriMedical
• Polyganics
• Stryker
• Synaptive Medical
• Synovis
• TheraCell
• Toyobo

Segments Covered in this Report

By Material

• Synthetic
• Biologic
• Hybrid

By Nerve

• Contact Guidance
• Channel Guidance
• Microtopography Guidance

By Electroactivity

• Electroactive
• Non-electroactive

By Application

• Peripheral Nerve Repair
• Spinal Cord Injury Repair
• Cranial Nerve Repair

By End-User

• Hospitals
• Clinics
• Research Institutes

By Region

• North America
  • U.S.
  • Canada
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Thailand
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Sweden
  • Denmark
  • Norway
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East and Africa (MEA)
  • South Africa
  • UAE
  • Saudi Arabia
  • Kuwait