Nerve Conduits, Wraps, Protectors, Cap, Connectors Market Size and Companies

Nerve Conduits, Wraps, Protectors, Cap, Connectors Market Size, Shares and Trends

The global nerve conduits, wraps, protectors, cap, connectors market size was estimated at US$ 255 million in 2023 and is projected to grow to US$ 691.98 million by 2034, rising at a compound annual growth rate (CAGR) of 9.5% from 2024 to 2034. The demand for nerve repair products is growing strongly due to the growing number of diabetes cases. Diabetes is a leading cause of nerve damage and requires nerve repair surgery.

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Market Overview

Nerve damage can occur in different manners. Depending on the way a nerve is damaged, different products can be used to repair it. For instance, conduits are pipes used to properly regulate nerves. Wraps are sheaths used for the protection and repair of partially damaged nerves. The coaptation location of severed nerves is relieved of stress by nerve connections. Assist coaptation in cable grafting, grafting, or direct repair. The coaptation location should be strengthened. Axonal regeneration of transected nerves is inhibited by nerve caps, which also isolate the site of nerve transection. Each of them has a different function and is in demand due to growing cases of diabetes. Diabetes slowly starts damaging nerves, and around 50% of diabetic patients deal with nerve damage and need nerve repair procedures at some point.

Nerve Conduits, Wraps, Protectors, Cap, Connectors Market Trends

• In October 2023, with the goal of funding $2.4 million over three years, the National Institutes of Health (NIH) awarded a $1.9 million grant to BioCircuit Technologies, a medical device firm located in Atlanta. The prize will be utilized to finish the creation and commercialization of Nerve Tape®, the first sutureless transected nerve healing technology.
• In May 2023, by gathering €50 million from both new and current international investors, ISSIUM announced the completion of a Series D round of funding. In particular, TISSIUM's ongoing first-in-human research of its first nerve repair product, COAPTIUM Connect, in Australia and many continuing regulatory processes are taking place at the same time as this most recent investment round.

Minimally Invasive Surgery is the Future of Nerve Repair

Minimally invasive surgery creates growth opportunities for the nerve conduits, wraps, protectors, cap, connectors market. As the name suggests, the surgery is conducted with minimal invasion of the body. Minimal invasion provides several benefits over traditional surgeries, which are reduced chances of infection, fast recovery & reduced hospital admission time, less pain after surgery, and reduced cost. Minimally invasive surgeries are gaining more popularity due to the use of robotic arms and robots for surgeries, which increase accuracy and efficiency.

Market Challenge: High Cost of Nerve Repair

The high cost of nerve repair products can be a significant restraining factor for the nerve conduits, wraps, protectors, cap, connectors market. Patients who cannot afford these products may opt for alternative treatments or therapies, leading to lower demand for nerve repair products. Moreover, healthcare systems in certain regions may not be able to provide adequate reimbursement for these products, further limiting their adoption.

Regional Insights

North America dominated the nerve conduits, wraps, protectors, cap, connectors market in 2023.

In North America, technological developments are what propel the market. Modern technology has made it possible to do nerve repair procedures using robots and minimally invasive procedures, which are superior to conventional techniques. Advanced infrastructure and equipment in the area also contribute to enhanced patient satisfaction and healthcare delivery.

In North America, the U.S. leads the nerve conduits, wraps, protectors, cap, connectors market because of its sophisticated healthcare infrastructure and rising diabetes rates. The peripheral neuropathy condition affects millions of people in the United States. The primary cause of peripheral neuropathy in the U.S. is diabetes. Nerve disorders in almost two-thirds of diabetics range from mild to dangerous. According to a study by Magellan Medical Technology Consultants, over 900,000 repair procedures annually result in approximately $2 billion in healthcare expenses, and over half a million Americans get peripheral nerve injuries that need surgical interventions.

People in Canada are also suffering from various neurodegenerative diseases which require medical attention. The government and other organizations are developing products and procedures to improve the quality of nerve repair.

The table shows the number of deaths that occurred in Canada from 2020 to 2022 due to various degenerative diseases of the nervous system. It indicates that Canada needs to act to resolve this, and different stakeholders can act to do so, promoting the growth of the market associated with nerve repair.

Asia Pacific is expected to grow at the fastest rate during the forecast period.

Diabetes may require a peripheral nerve conduit and is the primary cause of peripheral neuropathy. The primary driver of the nerve conduits, wraps, protectors, cap, connectors market's expansion is the rising incidence of diabetes.

The biggest number of traumatic spinal cord injury patients is seen in China. China, a major developing country with one of the largest populations in the world, has the potential to have a big impact on the worldwide rate of TSCI. A prevalent condition, peripheral neuropathy (PN), creates challenges for neurologists and doctors in terms of diagnosis and treatment. The total frequency of PN ranged from 5 to 2400 cases per 10,000 people in different community surveys conducted by epidemiological bodies in different parts of India.

Segmental Insights

By type, the nerve conduit segment dominated the nerve conduits, wraps, protectors, cap, connectors market in 2023. Using the nerve conduit bridging procedure, one may be able to circumvent the drawbacks of nerve grafting and direct nerve suturing. The perfect nerve conduit should be accessible, biodegradable, easily vascularized, low antigenic, porous for the flow of nutrients and oxygen, and free from long-term compression.

By type, the nerve wrap segment is anticipated to grow at a significant rate during the predicted period. Severe pain and disability can result from nerve scarring. Unpredictable outcomes are often obtained when the scarred nerve is treated. After neurolysis, a barrier wrapped over the damaged nerve may help stop epineural scarring from returning. The barrier should preferably be nondegradable and inert to prevent an inflammatory reaction.

For instance,

• In June 2024, Axogen, Inc. declared the release of Avive+ Soft Tissue MatrixTM, their newest product. Designed to be used as a soft tissue barrier, Avive+TM is a multi-layer, resorbable amniotic membrane allograft that offers tissue separation and temporary protection during the crucial stage of peripheral nerve recovery.

By application, the direct nerve repair segment held the largest share of the nerve conduits, wraps, protectors, cap, connectors market in 2023. A damaged nerve can be repaired, and its function can be restored in a variety of ways. Sometimes, the ends of a nerve that has been sliced sharply (for example, by a blade or glass) can be rejoined. This technique, known as direct nerve repair, is typically the first one a surgeon looks at.

By application, the nerve protection segment is expected to grow significantly during the forecast period. By reducing soft tissue attachment and preventing inflammatory macrophage infiltration, nerve protection helps to preserve and protect nerves that might not have been severed or clearly damaged. A safer environment for healthy nerve regeneration is produced by putting a barrier between the non-transected nerve and the soft tissue around it.

Recent Developments

• In September 2023, Axogen declared the complete release of its Axoguard HA+ nerve protector, which protects against peripheral nerve injuries.
• In April 2023, silkworm and spider silk tubes were demonstrated to be highly successful in repairing injured neurons by researchers from MedUni Vienna and the University of Oxford. The research may significantly broaden the spectrum of therapeutic options for nerve injury. The findings were reported in the journal Advanced Healthcare Materials.
• In March 2022, a resorbable implant called the NeuraGen® 3D Nerve Guide Matrix was introduced by Integra LifeSciences Holding Corporation to treat peripheral nerve discontinuities. NeuraGen 3D is a nerve repair tool that, in contrast to hollow neural conduits alone, produces the perfect environment that could enable a more thorough functional recovery after mid-gap nerve repair.

Top Companies in the Nerve Conduits, Wraps, Protectors, Cap, Connectors Market

• Axogen
• Shandong Junxiu Biotechnology
• Integra
• Collagen Matrix
• Accenray Biotech
• Synovis
• Checkpoint Surgical
• Regenity
• Guangzhou Zhongda Medical Equipment
• Toyobo
• Jiangsu Eton Biological
• Newrotex

Segments Covered in the Report

By Type

• Nerve Conduit
• Nerve Wrap
• Nerve Graft
• Others

By Application

• Direct Nerve Repair
• Nerve Protection

By Region

• North America
  • U.S.
  • Canada
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Thailand
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Sweden
  • Denmark
  • Norway
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East and Africa (MEA)
  • South Africa
  • UAE
  • Saudi Arabia
  • Kuwait