November 2024
The global plasma fraction market was estimated at US$ 32.75 billion in 2023 and is projected to grow to US$ 72.86 billion by 2034, rising at a compound annual growth rate (CAGR) of 7.54% from 2024 to 2034. There is a rising demand to create medicine products derived from plasma to treat rabies, tetanus, shock, and trauma. This factor is owing to the growth of the plasma fraction market.
Unlock Infinite Advantages: Subscribe to Annual Membership
Plasma fractionation is a separation process dividing different components of protein. Human blood plasma undergoes the process of fractionation for a variety of purposes including pharmaceutical research and to increase fractionation technologies. The prevalence of global diseases such as immunodeficiencies and genetic defects propels manufacturing companies to produce large quantities of high-quality medicine to meet the demand which also boosts the market of plasma fraction.
In the course of time, the scope of plasma fraction is expanding in the healthcare industry and therapeutics/biologics. Till now there are over 20 different proteins used. Plasma comprises water (91.5%), protein (7%) and salt (1.5%). Protein consists of Albumin (54%), immunoglobulin (38%), and Fibrinogen (7%).
With time immunoglobulin is leveraging its potential to treat immunodeficiencies, autoimmunity and many more. Immunoglobulin has a wide range of clinical applications in immune modulation. Initially, it was used to treat primary immunodeficiency disorders produced by insufficient development of antibodies. Currently, it is used as first-line therapy for genetic conditions such as immunodeficiency and X-linked agammaglobulinemia. Facilitation of immunoglobulin in inflammatory and autoimmune diseases such as Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy and still-person syndromes helps to calm the overactive immune responses by neutralizing cytokines and autoantibodies, fuelling the growth of plasma fraction market.
Despite the life-saving benefits of plasma and its derived protein, the high cost of plasma-derived medicine products is slowing the market growth. The increase in the cost of plasma has directly impacted the sustainability of PDMP production. During a pandemic, several countries were in shortage of immunoglobulin which caused rationing in the case of diseases. Even in countries such as Germany and the United States with higher supply of commercially sourced plasma has been observed at a shortage due to the increasing demand for PDMP production. In the last 5 years, the cost of plasma per litre has increased by 59.3% in Europe and 40.7% in the United States.
North America dominated the plasma fraction market in 2023. The growth of this region is attributed to rising numbers of exports of plasma from America. North America is the leading region for the largest exporter of plasma. The United States is one of the few countries to let companies pay for plasma, the U.S. supplies about 70% of the world’s plasma. The United States collects the majority of the world’s plasma for the production of plasma-derived medicinal products (PDMP).
Europe expected the grow at the fastest during the forecast period. The growth in this region is observed due to its strict regulations and restrictions. The rising shortage of plasma leads many countries to rely on imports to meet their medical needs. In Europe just 4 countries (Austria, Czechia, Germany, and Hungary) contribute more than 55% of total plasma collected goes under manufacturing.
By type, the immunoglobulins segment accounted for the highest market share in 2023. Plasma-derived Immunoglobulin is a significant part of the healthcare industry in the field of autoimmune inflammatory diseases. They are formed through the natural biological process in which the body is under recovery after an attack from an infectious organism (such as COVID-19). Oftentimes, immunoglobulins are the singular treatment to deal with rare conditions such as primary immunodeficiency.
The coagulation factors segment is expected to grow at the fastest rate during the projected period. The expansion of this segment is observed due to its use in the treatment of blood clotting diseases such as hemophilia and Von Willebrand’s disease.
By application, the hospital segment dominated the plasma fraction market by holding the largest market share. The dominance of this segment is credited to the use of plasma protein for patient treatment in hospitals. Plasma protein helps in recovering from burns, trauma, animal bites, shocks, major surgery, hepatitis, RH incompatibility, organ transplant, paediatric HIV, and liver conditions.
The retail pharmacy segment is expected to grow at the fastest rate in the plasma fraction market during the projected period. The expansion of this segment is observed due to the increasing number of human donors which provides enough supply of plasma. A rise in the number of patients eligible to be treated by plasma-derived therapy also increases the supply and sell in the retail pharmacy segment.
By Type
By Application
By Region
November 2024
November 2024
November 2024
November 2024
Deepa has certified the degree of Master’s in Pharmacy in the Pharmaceutical Quality Assurance department from Dr D.Y. Patil College of Pharmacy. Her research is focused on the healthcare industry. She is the author or co-author of four Review Articles, which include Solid dispersion a strategic method for poorly soluble drugs and solubility improvement techniques for poorly soluble drugs, Herbal Drugs Used In Treatment Of Cataracts, Nano sponges And Their Application in Cancer Prevention and Ayurvedic Remedies of Peptic ulcer. She has also published a Research Article on the Formulation and Evaluation of Mucoadhesive Tablets of Miconazole cocrystal which was published in GIS Science Journal Volume 9 Issue 8. Her passion for secondary research and desire to take on the challenge of solving unresolved issues is making her flourish is the in the research sector.
Annual Access, Limitless Research! Unlock all market research reports with our annual subscription. Stay on top of market trends and crucial insights year-round!
2500+
Client Queries in 20235000+
Insights Published60+
Consulting Projects Per Year40+
Analysts