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November 2024
The global cell cryopreservation market size is calculated at US$ 11.48 in 2024, grew to US$ 13.89 billion in 2025, and is projected to reach around US$ 77.52 billion by 2034. The market is expanding at a CAGR of 21.05% between 2024 and 2034. Cell cryopreservation is used in various health-related applications and, hence, is in high demand. With growing research in healthcare, the demand for cell cryopreservation is growing to increase significantly in the market in the future.
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Cryopreservation is a technique used to preserve the fine structure of cells by keeping biological material in a suspended animation condition at freezing temperatures for an extended amount of time. From the preservation of hematopoietic tissue for transplantation to the preservation of pluripotent stem cells for in vitro fertilization, cryobiology and cryopreservation provide several benefits for a variety of pharmaceutical applications. The development of new biologics, like vaccines, has benefited greatly from the cryopreservation of cell lines. It is also essential for biotechnology, clinical assays, and research, as well as for a number of targeted therapies, such as autologous stem cell therapy, which uses cell freezing to preserve stem cells, such as those extracted from bone marrow.
In recent years, artificial intelligence (AI) has advanced quickly, moving from the experimental stage to the implementation stage across a range of industries, including health. Cryopreservation is one area of the biological sciences where artificial intelligence has proven advantageous. The application of artificial intelligence in various contexts has several advantages. These include enhancing security and ensuring the best possible storage for biological items. Bioinformatics also benefits from it. AI steps in here by providing a continuous, real-time monitoring system for cryopreserved samples with unmatched precision. AI-driven systems utilize sophisticated sensors and machine learning algorithms to continually monitor the storage environment and identify even the smallest departures from ideal conditions.
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Need for Prolonged Storage
Numerous essential uses for cell cryopreservation exist in the study of cell separation. The capacity to store important cells for extended periods of time for research purposes and to maintain experimental viability after thawing is the major benefit of cryopreservation. Researchers may more effectively arrange their investigations by using cryopreservation to extend the storage durations of well-known cell sources, such as leukopaks, and eliminate the need for fresh cell delivery. Successful cryopreservation of stem cells is a promising first step in tissue engineering and other next-generation biomedical objectives, in addition to more readily available cell sources.
Ice Crystal Formation
The formation of ice crystals inside the cells, which might harm the cells, is one of the main drawbacks of cryopreservation. Cell viability is impacted by the use of inappropriate cryoprotectants as well. Cellular dehydration and extracellular ice production can result from water movement.
Automation in Cryopreservation
Automation is revolutionizing cryopreservation. Labs can reduce a large portion of the human error that comes with manual handling by using robotics and automated storage systems. Researchers and biological materials are protected by automated cryopreservation systems, which can extract samples with extreme precision while lowering the possibility of unintentional warming or contamination. Efficiency is also greatly increased by automation, particularly when laboratories handle thousands or even millions of samples instead of just hundreds. By guaranteeing consistent sample handling and tracking, automation can help with regulatory compliance.
By product, the consumables segment dominated the cell cryopreservation market in 2023. Consumables are small instruments, tools, and containers that are used for cryopreservation. These consumables should be capable of withstanding lower temperatures and should not react to freezing media and cell cultures. When performing research, choosing the appropriate lab equipment is crucial. Increases in the demand for plasticware, funding, and investment from both public and private entities for research and diagnostic services, the prevalence of chronic diseases, and the number of research laboratories are the main drivers of growth in the consumables and instrumentation sector. Additionally, the demand for laboratories at academic institutions increased as a result of students' growing interest in innovation for the creation of new treatments and research projects.
By product, the freezing media segment is estimated to witness the fastest CAGR in the cell cryopreservation market during the forecast period of 2024-2034. Media is a liquid solution used for storing viable cells. Freezing media is slightly different from regular media, as freezing media should support the viability of cells at lower temperatures. Freezing media consists of buffers and necessary nutrients. The media also prevents the formation of ice crystals and cell damage during cryopreservation.
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By application, the stem cells segment held the major share of the cell cryopreservation market in 2023. For many years, stem cells have been employed in therapeutic settings. In recent years, stem cell banking and cryopreservation have grown in popularity. On the other side, those who want to get stem cell treatment or lessen the effects of an illness may find that stem cell banks are an invaluable resource. Stem cells may help heal injured tissues and, in certain situations, even help treat illnesses like cancer.
By application, the oocytes and embryotic cells segment is estimated to grow at the fastest rate in the cell cryopreservation market during the predicted timeframe. Fertility preservation and maximizing the safety and effectiveness of ovarian stimulation cycles in an IVF therapy depend on the successful cryopreservation of oocytes and embryos. Slow-freezing and vitrification are the two cryopreservation techniques that are often employed.
By end-use, the IVF clinics segment held the largest share of the cell cryopreservation market in 2023. According to a new WHO research released today, infertility affects a significant number of people throughout their lives. Approximately 1 in 6 adults globally, or 17.5% of the total population, are infertile, highlighting the critical need to expand access to high-quality, reasonably priced reproductive treatment for those who require it.
By end-use, the biobanks segment is expected to achieve the fastest CAGR in the cell cryopreservation market during the forecast period. For the benefit of all people, biobanking has been a vital component of life-science research and development, and it has greatly advanced biotechnology, healthcare, disease prevention and control, and bio-conservation. Biobanks have been able to streamline procedures associated with specimen processing and sampling thanks to automation. Industry-wide software development is ongoing with the goal of enabling biobanks to manage clinical data, permission paperwork, and inventory and expenditures.
North America dominated the cell cryopreservation market share by 41% in 2023. North America's cell cryopreservation market stands out due to its emphasis on technical innovation and extensive cryopreservation technique research. Because of the rising popularity of personalized medicine and a robust biomedical research industry, the area is seeing an increase in demand for cryoprotectants and sophisticated freezing processes. The strategic alliances between academic institutions and commercial businesses are responsible for the rapid development of cryopreservation technology in North America.
The average cost of an IVF cycle in the United States is between $12,000 and $17,000, and it can reach $25,000 if medication is required. The percentage of live births that use ART rises with the age of the mother: in 2023, 9% of live births for women aged 40 to 45 involved ART use, while for women aged 45 and over, ART was used in almost one-third of live births. ART use also varies geographically in the U.S. States, with the highest number of infants born with the use of ART each year, including California (more than 11,000), New York (nearly 9,000), Texas (more than 7,000), New Jersey, and Illinois (5,500).
Asia Pacific is estimated to grow at the fastest rate during the forecast period. With a discernible focus on rising biobanking operations and the increasing impact of regenerative medicine, the Asia-Pacific cell cryopreservation market is displaying dynamic patterns. The need for cryopreservation technology is being driven by a flourishing healthcare industry and increased knowledge of stem cell uses in the region's expanding economies. Asia is seeing an increase in the use of automated cryopreservation systems, indicating a progressive approach to the use of technology in cell preservation. Furthermore, the cell cryopreservation market in India grew at the quickest rate in the Asia-Pacific area, while the market in China had the biggest market share.
A number of variables, including later marriages, older pregnancy ages, rising infertility rates, higher disposable money, and increased knowledge of infertility treatments, have contributed to the notable growth in In Vitro Fertilization (IVF) services in India.
In October 2024, the Board of Directors authorized the payment of a regular quarterly cash dividend to its shareholders of record as of the close of business on November 15, 2024, at an initial rate of $0.25 per share of common stock, according to a statement released by Cryo-Cell International, Inc. November 29, 2024, is the anticipated date of the dividend payment. The dividend policy will be regularly reviewed by the Board of Directors, taking into account the company's cash flows, profitability, and potential alternative uses and access to capital.
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