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Tissue Engineering Market | Size | Trends | Shares | Growth

Tissue Engineering Market Size to Grow at 14.35% by 2033

The report covers Tissue Engineering Market Growth Segments into several products are categorized into scaffolds and tissue grafts, with material into synthetic, biological, collagen, hydrogel, stem cells and others, while tissue grafts into allograft, autograft, synthetic grafts, xenograft and other products. Materials are segmented into synthetic and biologically derived categories. Applications include orthopedics and musculoskeletal disorders, dermatology and wound care, dental disorders, cardiovascular diseases and others. The end-users are hospitals, specialty centers and clinics and ambulatory surgical centers. The report offers the value (in USD Billion) for the above segments.

Tissue Engineering Market Size, Shares and Growth Application Report

The global tissue engineering market size was estimated at US$ 17.05 billion in 2023 and is projected to grow to US$ 64.11 billion by 2033, rising at a compound annual growth rate (CAGR) of 14.35% from 2024 to 2033. The need for tissue engineering solutions that can replace or repair damaged tissues has been fueled by the rising prevalence of chronic illnesses, including diabetes, cardiovascular disease, and orthopedic problems.

Tissue Engineering Market Revenue 2023 - 2033

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Key Takeaways

  • By region, North America dominated the tissue engineering market in 2023.
  • By region, Asia Pacific is expected to grow at the fastest rate during the forecast period.
  • By product, the scaffold segment held the dominant share of the market and is expected to grow at the fastest rate during the forecast period.
  • By material, the synthetic segment held the largest share of the market and is expected to hold the dominant position during the forecast period.
  • By application, the orthopedics & musculoskeletal segment dominated the market in 2023.
  • By end-user, the hospitals segment dominated the market in 2023.

Industry at a Glance

The field of biomaterials development gave rise to the tissue engineering market, which now includes the process of creating functional tissues using scaffolds, cells, and biologically active chemicals. Creating functional constructions that preserve, repair, or enhance damaged tissues or whole organs is the aim of tissue engineering. The challenges surrounding donor organs and tissues, as well as the shortcomings of the available treatments for clinical tissue damage, may be resolved by tissue engineering. The reconstruction of tissues (such as tendons, vascular, nerve, bone, and cartilage) and other organs (such as the kidney, pancreas, and liver) is only one example of the variety of options available for producing replacement body parts.

Top Companies in the Tissue Engineering Market

  • Baxter International, Inc.
  • ReproCell, Inc.
  • RTI Surgical, Inc.
  • Stryker Corporation
  • Tissue Regenix Group plc
  • Athersys, Inc.
  • ACell, Inc.
  • Medtronic
  • Organogenesis Holdings Inc.
  • Integra LifeSciences Corporation
  • B. Braun
  • Becton Dickinson and Company
  • AbbVie (Allergan)
  • Bioserve
  • Zimmer Biomet Holdings, Inc.
  • TissueLabs

Recent Development by TissueLabs in the Tissue Engineering Market

Company Name TissueLabs
Headquarters Manno, Switzerland, Europe
Recent Development In March 2024, with its headquarters located in Manno, in the canton of Ticino, TissueLabs is a firm that specializes in producing synthetic organs and tissues for medicinal uses. The company recently raised $800,000 in pre-seed funding. In a news statement, it was said that the Brazilian venture capital company Mergus Ventures led the fundraising round, with participation from individual investors, MIT Angels, and other funds. A portion of the funds has been set aside expressly for Bellinzona's new hub.

Recent Development by Bioserve in the Tissue Engineering Market

Company Name Bioserve
Headquarters Yokohama, Japan, Asia Pacific
Recent Development In July 2024, the innovative stem cell products that Bioserve India is proud to introduce to the Indian market are now available. These new offerings from REPROCELL are intended to foster scientific innovation and medication development, as well as improvements in the Indian market for regenerative medicine and therapeutic discoveries. The stem cell market is a fast-expanding sector of the economy that offers a vast array of goods and services. Many businesses within the stem cell market are involved in vital tasks, including production, distribution, and research & development related to stem cell treatment.

Increasing Prevalence of Chronic Conditions is Driving the Tissue Engineering Market

Another important component of regenerative medicine that is revolutionizing the treatment of chronic illnesses is tissue engineering. It includes growing synthetic organs and tissues in the lab for use in transplants or fixing the body's damaged tissues. The treatment of diabetes has benefited greatly from one of tissue engineering's biggest advances.

Chronic illnesses, such as diabetes, heart disease, stroke, and cancer, continue to be among the world's top causes of morbidity and mortality. Chronic illness is expected to cost the world economy $47 trillion by 2030. With an estimated annual cost to the nation of $1 trillion, chronic illness places a significant financial strain on the American healthcare system. The World Health Organization (WHO) estimates that noncommunicable diseases (NCDs) cause 41 million deaths globally each year, or 74% of all deaths. 17 million people die from NCDs before they become 70 years old each year; 86% of these premature deaths occur in low- and middle-income countries.

Global Deaths due to Chronic Diseases Each Year

Challenges in Scaffold Preparation Restraints the Tissue Engineering Market Growth

Forming scaffolds with the appropriate parameters to mimic an appropriate microenvironment for cells is a demanding task since it is hard to manage the internal pore structure, porosity, and pore connectivity of the scaffolds in these ways. For rapid deployment in clinical applications, scaffold manufacturers should prioritize both appropriate biological characteristics and economical scaffold production. In addition, leftover organic solvents from the scaffolds can cause cell harm.

Development of Smart Polymers Creates Growth Opportunity for the Tissue Engineering Market

Smart polymers could provide a solution to the issues with the scaffolds now used in tissue engineering. Tissue engineering uses smart polymers that can respond to stimuli, change shape, or heal themselves. With four-dimensional (4D) printing, objects that are three-dimensional (3D) can have their shapes altered in response to temperature, moisture, water, pH, light, and other environmental factors over time. Recently, a lot of attention has also been paid to this technology. It is expected that further study into the synthesis of smart hydrogels with simultaneous shape memory and self-healing properties will be conducted in the subsequent years.

Report Highlights

Product Insights

The scaffold segment held the dominant share of the tissue engineering market and is expected to grow at the fastest rate during the forecast period. The structural support for cell adhesion and subsequent tissue formation is provided by scaffolds, which are often composed of polymeric biomaterials. In order to replace or repair damaged or destroyed tissues, tissue-engineering scaffolds composed of different biomaterials have been produced throughout the past ten years.

For instance,

  • In June 2023, an animal-derived Class D Biomedical Device that may quickly mend skin wounds at a low cost with minimal scarring has been approved by the Indian Drugs Controller. It is the first tissue engineering scaffold from mammalian organs to be produced nationally.

Material Insights

The synthetic segment held the largest share of the tissue engineering market and is expected to hold the dominant position during the forecast period. Polyesters, polyanhydrides, polyphosphazenes, polyurethane, and poly (glycerol sebacate) are examples of synthetic biodegradable polymers that are frequently utilized in tissue engineering. The synthetic biodegradable polymers that are most commonly utilized in tissue regeneration are aliphatic polyesters. Typically, synthetic polymers are immune system-safe, have a more flexible processing degree, and have a regulated structure.

Application Insights

The orthopedics & musculoskeletal segment dominated the tissue engineering market in 2023. Bone diseases, tumor removal, fractures, and infections can all result in bone abnormalities. One promising method for treating clinical needs for bone regeneration and repair is tissue engineering. The construction of 3D scaffolds, which offer structural support for the formation of new bone, is the primary goal of tissue engineering in orthopedics. The therapy of orthopedic pathologies will be on tissue engineering with biomaterials in the future. Due to its special qualities, silk is a promising biopolymer in these applications for hard and soft tissue engineering.

For instance,

  • In March 2024, For the treatment of osteoarthritis in the knee, the FDA authorized PCRX-201, also known as enekinragene inzadenovec, as Regenerative Medicine Advanced Therapy (RMAT). This statement was made today by Pacira BioSciences, Inc., a leader in the fields of non-opioid pain treatment and regenerative health solutions. The company is developing PCRX-201, a novel intra-articular helper-dependent adenovirus (HDAd) gene therapy product candidate that codes for IL-1Ra.

End-user Insights

The hospitals segment dominated the tissue engineering market in 2023. All hospital medical equipment is managed by the Department of Biomedical Engineering. In order to ensure the safe and efficient use of healthcare technology, the biomedical engineer provides support to the healthcare providers during the technology acquisition process. This support is provided through a well-designed program of user training, maintenance, and quality assurance. To provide the best possible care, hospitals stock their facilities with operational, calibrated, and safe medical equipment. This helps minimize patient discomfort and aggravation from broken equipment and lost time due to equipment malfunction.

Regional Insights

North America dominated the tissue engineering market in 2023. A bigger tissue engineering market share is also a result of the region's high healthcare expenditures, easy access to government and private funding, and cutting-edge chronic illness diagnosis and treatment technology. The rise in popularity of stem cell therapy, the aging population, the availability of both government and private funding, improved chronic illness diagnosis and treatment technology, and high healthcare costs are all contributing factors to the growth. The region's dominant position in the market is a result of several forces working together.

In the North American region, the U.S. has the most tissue engineering market share. With the assistance of important market participants and government support, the U.S. contributes to the expansion. A call for proposals that use the International Space Station (ISS) National Laboratory to further tissue engineering and mechanobiology research is being funded by the U.S. National Science Foundation (NSF). NSF will finance up to $1.6 million through this proposal for a number of projects that aim to make use of the orbiting laboratory.

The National Science Foundation (NSF) advances fundamental research in all branches of science and engineering, therefore driving national progress. In order to maintain American leadership in research and innovation around the world and to promote the creativity of researchers, NSF provides facilities, tools, and funds. NSF funding, which has a $9.5 billion budget for the fiscal year 2023, is distributed to almost 2,000 schools, universities, and other institutions in all 50 states. Over 40,000 competitive proposals are received by NSF annually, and approximately 11,000 new awards are made.

Asia Pacific is expected to grow at the fastest rate during the forecast period. Japan has become a pioneer in tissue engineering technology development. The market for tissue engineering is also expanding due to the rising incidence of clinical illnesses, such as cancer, in Asia. Tissue engineering market growth is also fueled by factors like the development of 3D bioprinting technology and the expansion of medical tourism in the area.

Together, the government and business community in Japan are implementing ambitious regulatory reform and actively encouraging international firms to invest in order to further this field. With over JPY 1 billion (USD 9 million) in financial support available, the Japan External Trade Organization (JETRO) has taken the lead in efforts to assist foreign businesses that invest in regenerative medicine in Japan.

Recent Developments in the Tissue Engineering Market

  • In March 2024, the U.S. Department of Health and Human Services (HHS) department that oversees the Advanced Research Projects Department for Health (ARPA-H) launched the Personalized Regenerative Immunocompetent Nanotechnology Tissue (PRINT) initiative. The goal of PRINT is to 3D print customized, on-demand organs without the need for immunosuppressive medications by utilizing cutting-edge bioprinting technology in conjunction with a regenerative medicine methodology.
  • In October 2023, with the introduction of CELLINK Vivoink, the first medical-grade bioink created specifically to assist researchers on their clinical translational journey, CELLINK, a leader in the world of bioprinting technologies, announced a groundbreaking breakthrough in the fields of regenerative medicine and tissue engineering. CELLINK Vivoink is a game-changer in the bioprinting sector because of its exceptional printability, mechanical stability, and cell survival.
  • In June 2023, Azusa Pacific University was awarded funds to construct a cutting-edge tissue engineering research center at the Segerstrom Science Center. Students can conduct research in this lab to position themselves for success in the quickly expanding field of product development in pharma and biopharma.

Segments Covered in the Report

By Product

  • Scaffold, By Material
    • Synthetic Material
    • Biological Material
      • Collagen
      • Hydrogel
      • Stem Cells
      • Others
  • Tissue Grafts, By Type
    • Allograft
    • Autograft
    • Synthetic Grafts
    • Xenograft
  • Other Products

By Material

  • Synthetic Material
  • Biologically Derived Material

By Application

  • Orthopedics & Musculoskeletal Disorders
  • Dermatology & Wound Care
  • Dental Disorders
  • Cardiovascular Diseases
  • Others

By End User

  • Hospitals
  • Specialty Centers and Clinics
  • Ambulatory Surgical Centers

By Region

  • North America 
    • U.S.
    • Canada
  • Europe 
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Sweden
    • Denmark
    • Norway
  • Asia Pacific 
    • China
    • Japan
    • India
    • South Korea
    • Thailand
  • Latin America 
    • Brazil
    • Mexico
    • Argentina
  • Middle East and Africa (MEA) 
    • South Africa
    • UAE
    • Saudi Arabia
    • Kuwait

Relevant Report

How Cell Separation Technology Enhances Therapeutics, Diagnostics and Personalized Medicine?

The cell separation is expanding rapidly due to its diverse applications across several fields, including therapeutics, diagnostics and personalized medicine by isolating specific cells from mixed samples. Cell separation, also known as cell isolation or sorting, involves extracting specific cell populations from a mixture of different cells. This process allows scientists to focus on isolated cells by minimizing the influence of other cell types, which is crucial for accurate research and analysis.

Isolated cells play a significant role in life science research, enabling scientists to conduct precise tests and develop targeted treatments. One of the key factors driving the growth of the cell separation market is the increasing demand for personalized medicine. This technology also contributes to creating effective and scalable treatment methods for large populations.

  • The global cell separation market size was valued at approximately USD 9.10 billion in 2023 and is expected to reach USD 23.56 billion by 2033. This growth represents a compound annual growth rate (CAGR) of 9.98% from 2024 to 2033. The increasing prevalence of infectious and chronic diseases is a major factor driving this market expansion.
  • Insight Code: 5188
  • No. of Pages: 150+
  • Format: PDF/PPT/Excel
  • Published: July 2024
  • Report Covered: [Revenue + Volume]
  • Historical Year: 2021-2022
  • Base Year: 2023
  • Estimated Years: 2024-2033

Meet the Team

Kesiya Chacko is a healthcare market research expert with 4+ years of experience, specializing in analyzing industry trends, assessing market opportunities, and providing actionable insights for businesses in healthcare sectors.

Learn more about Kesiya Chacko

Aditi Shivarkar, with 14+ years of healthcare market research experience, ensures the accuracy, clarity, and relevance of reports. Her expertise helps businesses make informed decisions and stay competitive in healthcare sectors.

Learn more about Aditi Shivarkar

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FAQ's

Starting with the selection, isolation, and culture of primary (progenitor or stem) cells, the tissue engineering procedure entails a number of steps, including seeding and cultivation, inducing the cells to differentiate into specific phenotypes and designing appropriate scaffolds that consider factors like porosity, interconnectivity, surface characteristics and process-specific material selection.

Tissue engineering and study on self-healing, in which the body employs its own mechanisms to regenerate cells and reconstruct tissues and organs—sometimes with the assistance of external biological material—are both included in the vast topic of regenerative medicine.

National Engineering and Regenerative Medicine, National Institutes of Health, NIST, NSF, The Government of Japan.